英文名稱    DUSP22    

中文名稱    雙特異性磷酸酶22抗體    

別    名    Dual specificity protein phosphatase 22; JNK stimulatory phosphatase 1; JSP 1; JSP1; LMW DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; MKPX; DUS22_HUMAN.    

供應(yīng)商     遠(yuǎn)慕生物

研究領(lǐng)域    細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  細(xì)胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  激酶和磷酸酶      

抗體來源    Rabbit    

克隆類型    Polyclonal    

交叉反應(yīng)    Human, Mouse, Rat, Cow, Rabbit,     

產(chǎn)品應(yīng)用    WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 雙特異性磷酸酶22抗體（石蠟切片需做抗原修復(fù)） 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.    

分 子 量    21kDa    

細(xì)胞定位    細(xì)胞核 細(xì)胞漿     

性    狀    Lyophilized or Liquid    

濃    度    1mg/1ml    

免 疫 原    KLH conjugated synthetic peptide derived from human DUSP22/JSP1    

亞    型    IgG    

純化方法    affinity purified by Protein A    

儲 存 液    Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4    

保存條件    Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.    

雙特異性磷酸酶22抗體產(chǎn)品介紹    background:

Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase /c-Jun N-terminal kinase (SAPK/JNK)

Function:
Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) (By similarity).

Subunit:
Monomer. 

Subcellular Location:
Cytoplasm (By similarity). Nucleus (By similarity).

Tissue Specificity:
Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas. 

Post-translational modifications:
Myristoylation regulates subcellular location, and is necessary for activation of JNK. 

Similarity:
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 
Contains 1 tyrosine-protein phosphatase domain. 

Database links:
UniProtKB/Swiss-Prot: Q9NRW4.1